Cognitive Impairment in Depression a Systematic Review and Meta-analysis

Review

doi: 10.1192/bjp.bp.114.148130.

Psychological treatments for depression and anxiety in dementia and mild cognitive impairment: systematic review and meta-analysis

Affiliations

  • PMID: 26429684
  • PMCID: PMC4589662
  • DOI: 10.1192/bjp.bp.114.148130

Gratuitous PMC article

Review

Psychological treatments for depression and anxiety in dementia and balmy cognitive impairment: systematic review and meta-analysis

Vasiliki Orgeta  et al. Br J Psychiatry. 2015 Oct .

Free PMC article

Abstract

Groundwork: Anxiety and low are common in people with dementia and mild cognitive harm (MCI), but at that place is doubtfulness about the effectiveness of both pharmacological and psychological therapies.

Aims: To evaluate the evidence of effectiveness of psychological treatments in treating depression and anxiety in people with dementia and MCI.

Method: We carried out a systematic review and meta-analysis of randomised controlled trials (RCTs) of psychological handling versus usual intendance in people with dementia and MCI. Principal outcomes were symptoms of feet and depression. Secondary outcomes were quality of life, ability to perform daily activities, neuropsychiatric symptoms, knowledge and caregivers' self-rated depressive symptoms.

Results: We included half dozen RCTs, involving 439 participants with dementia, which used cognitive-behavioural therapy, interpersonal therapy, counselling or multimodal interventions including a specific psychological therapy. We establish beneficial effects for both depression and anxiety. Overall, the quality of the evidence was moderate for depression and low for anxiety, due to the methodological limitations of the studies nosotros identified and the limited number of trials.

Conclusions: The prove from vi RCTs suggests that psychological treatments are effective in reducing symptoms of depression and anxiety for people with dementia. There is a need for loftier-quality, multicentre trials including standardised, well-defined interventions.

Disharmonize of interest statement

Declarations of interest

A.Q., A.S. and Yard.O. are investigators in one of the included studies.

Figures

Fig. 1
Fig. 1

Review and meta-assay flow diagram.

Fig. 2
Fig. 2

Forest plot of psychological treatment versus treatment as usual. Outcome: ane.1 Depression.

Fig. 3
Fig. iii

Forest plot of psychological treatment versus treatment as usual. Result: ane.2 Anxiety RAID. RAID, Rating Anxiety in Dementia scale.

Fig. 4
Fig. iv

Forest plot of psychological treatment versus handling every bit usual. Event: 1.3 Anxiety (self-ratings).

Fig. 5
Fig. 5

Forest plot of psychological treatment versus treatment equally usual. Consequence: 1.four Anxiety NPI-A. NPI-A, Neuropsychiatric Inventory-Anxiety.

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Source: https://pubmed.ncbi.nlm.nih.gov/26429684/

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